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Becker ML, Visser LE, van Schaik RH, Hofman A, Uitterlinden AG, Stricker BH (2009) Genetic variation in the organic cation transporter 1 is associated with metformin response in patients with diabetes mellitus

Understanding how these medications work throughout the body is important when considering potential side effects, as GLP-1 receptors are present in multiple organ systems beyond the pancreas, including the gastrointestinal tract, cardiovascular system, and central nervous system

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Notably, coordinated actions of GGT and ChaC1/ChaC2 have been identified in modulating GSH levels both within and outside the cell (11)

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2017;169(1):132-147.e16