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Sublingual administration, which bypasses the gastrointestinal tract, appears to be equally effective as IM injections while being less invasive and more cost-efficientparticularly in patients with atrophic gastritis, post-gastrectomy status, or conditions that impair intrinsic factor-mediated absorption, where long-term intervention is often required

Sections were fixed in ice-cold 0.5% glutaraldehyde (w/v, PBS) for 15 min and washed with 1 mM MgCl 2 /PBS (pH 6.0) for 5 min

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Manufactured in a facility that processes products containing milk, soy, egg, and wheat

304 Calcium signaling Intracellular calcium could originate from the opening of plasma membrane calcium channels, such as voltage-gated and ligand-gated calcium channels, and the release of organelles like the ER and mitochondria

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