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This dramatic increase in weight reduction capabilities naturally leads to speculation around additional health benefits for multiple conditions, including diabetes, cardiovascular, sleep apnea, and others for which medical devices and procedures are often part of management and treatment regimens

Maintain adequate fluid intake and contact your GP if you cannot keep fluids down or experience signs of dehydration

They are grounded in endogenous biology, often supported by convergent evidence across species and experimental modalities, and frequently act at integrative nodes that coordinate multiple physiological processes

The SELECT trial (NEJM 2023) showed semaglutide 2.4 mg reduced major adverse cardiovascular events by approximately 20% versus placebo in non-diabetic adults with obesity and established cardiovascular disease

It is a balancing act with which we are entrusted every day

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