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C., Grant, C

The metabolic profile of autistic patients has been shown to be abnormal with elevated biomarkers that indicate chronic oxidative stress and evidence that GSH synthesis may be insufficient to maintain redox homeostasis [14, 15]

The level of oxidative stress, quantified by the oxidative stress markers, has been found elevated in aging individuals or people with bad lifestyles, taking unhealthy food, smoking, drinking alcohol, lack of physical exercise, and genetic predisposition

doi: 10.2337/dc19-0749 58 O'NeilPMBirkenfeldALMcGowanBMosenzonOPedersenSDWhartonSet al

Alternatives such as metformin, lifestyle modification, and bariatric intervention should be prioritized in preconception care

00:25:41 Don Weinberger: Right