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This is because of its FDA approval and 10+ year safety profile as well as multiple proven benefits for metabolism and cardiovascular risk with speculative/accumulating evidence for dementia prevention

For the last 50 years, bariatric surgery has been the most effective treatment for obesity resulting in approximately 25% weight loss, whilst also improving the control of type 2 diabetes mellitus (T2DM) and reducing cardiovascular and cancer deaths

The ongoing TRIUMPH Phase 3 programme is expected to generate the robust, large-scale efficacy and safety data required for a regulatory submission

Strategy 3: address GI symptoms aggressively Do not accept persistent nausea as an inevitable cost of treatment

Less body mass = less blood volume needed = lower pressure required to perfuse tissues

(2) written in English