In this article: When the first weight loss GLP-1s hit the scene liraglutide and semaglutide they mimicked a single hormone (glucagon-like peptide-1)
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It does this by: Increasing insulin release when blood sugar is high Reducing the livers release of stored sugar Slowing digestion so that sugar enters the bloodstream more slowly When blood sugar becomes more stable, the kidneys also filter fewer excess sugars
Topamax has been used for weight loss in some individuals with binge eating disorder (BED), and though it can be effective in reducing weight, it doesnt treat the underlying issues of BED
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