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Similarly, double-heterozygous-mutant worms carrying both the D72G and G247Vfs*6 alleles (modeling the two patients carrying the compound heterozygous variants) showed no embryonic lethality, even under prior starvation (Fig

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Additionally, research methodologies such as computational modeling might help refine hypotheses regarding receptor binding dynamics and intracellular signaling modulation

A provider should help determine which option is appropriate