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However, these single amino acid polymorphisms significantly affect ApoE functionality, leading to isoform-specific variations in structure that influence its binding properties with lipids and receptors, as well as its propensity for oligomerization and stability (Yamazaki et al., 2019
Hippocampus (2014) 24:23948
R.RaghavendraA
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This alternative route shows why highly lipophilic compounds (with log P values above 5) show better bioavailability through lymphatic transport
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