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Science 317 , 807810 (2007)

Data on the long-term safety of DMTs in older people with MS are unavailable, which is a critical concern given that adverse events particularly serious infections, risk of cancer and emergency hospital admissions increase with age 10,101

Purine nucleoside phosphorylase deficiency induces p53-mediated intrinsic apoptosis in human induced pluripotent stem cell-derived neurons

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Higher doses consistently led to greater weight loss across all time points

ACA/individual plans generally exclude it