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Who should consider tirzepatide with B12 and who should avoid it Ideal candidates for tirzepatide with B12 include adults with obesity (BMI 30) or overweight with comorbidities (BMI 27 with conditions like type 2 diabetes, hypertension, or dyslipidemia)

Rhythm Pharmaceuticals, 2024, "Rhythm Pharmaceuticals announces first patients dosed in Phase 2 Trial evaluating oral MC4R agonist LB54640 in hypothalamic obesity." Accessed 19 th May 2025

The crystallization process disrupts molecular integrity

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The authors also point out that in some rare genetic disorders of B12 metabolism, the active forms may be required, and that smokers, who tend to have an excess of thiocyanate in their blood, may benefit from a taking a form other than cyano-B12

And our hormones are severely depleted already from this chemical soup