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The bottom line on research Most existing findings come from lab and animal studies

Natural history of nonoperatively treated symptomatic rotator cuff tears in patients 60 years old or younger

Clinical Study 2

Vitamin B12 stimulates hematopoiesis, participates in the formation of creatine (a source of energy for muscle tissue), participates in the biosynthesis of acetylcholine, has a positive effect on the nervous system, stimulates fat metabolism and carboxylic acid metabolism, normalizes digestion, promotes methionine biosynthesis

Some users maintain low-dose protocols long-term for ongoing joint and tissue support

Special caution is warranted in certain contexts even if not formal contraindications