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From pain catastrophising to multidimensional psychological distress: unravelling the complexity of difficult-to-treat psoriatic arthritis

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Clinical studies show that lower doses of GLP-1 agonists are highly effective at reducing hemoglobin A1c (which indicates the average blood sugar level over the past 2-3 months), improving insulin sensitivity, and directly addressing the metabolic dysregulation often associated with estrogen decline and perimenopausal weight gain, helping to stabilize energy levels and reduce fat-storage signaling