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If these agents reduce OSA severity independently of weight loss, they may open an entirely new therapeutic chapter for patients with obesity hypoventilation and REM-related OSA

While synthetic human growth hormone (HGH) can be effective, it's expensive, suppressive, and banned in nearly every sport

Lastly, the primary end point in PIONEER 6 (the CVOT) was a time to event analysis

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Juan Francisco Merino-Torres: provided expert clinical opinion and critical revision of the manuscript for important intellectual content