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Our patch-clamp electrophysiology results corroborate these findings, demonstrating that GLP-1RAs directly activate DMH GLP-1R neurons, which in turn send inhibitory projections to ARC AgRP/NPY neurons [69]

These approaches remain largely investigational and are not widely used in mainstream medicine

Over three decades of research have revealed a pharmacological profile that includes cardioprotection, neuroprotection, tissue repair, metabolic modulation, and immune support

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