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Classical antioxidants, such as N-acetyl-L-cysteine (NAC) and melatonin, reduce oxidative stress and slow mouse oocyte aging [351,352,353]

The Importance of Antioxidants During Pregnancy Pregnancy is a time of increased oxidative stress due to the rapid changes occurring in the body

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They found that DDD therapeutically targets AS by enhancing mitochondrial function through the HIF-1 signaling pathway, reducing ROS levels, and modulating GPX4, Bcl2, and Bax protein levels, thereby benefiting AS and hyperlipidemia (Wu et al., 2023a)

The result: sustained activation of the same receptors, producing meaningful and durable weight loss and blood-sugar improvement