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Of note, almost half of patients treated with GLP-1-RAs also had pre-existing migraine as comorbidity (26.7% in the UCWM group), which could predispose them to worse (rather than better) headache outcomes [31], providing additional evidence of a favorable effect of GLP-1-RAs on headache improvement

A recent analysis of FDA adverse event reporting system (FAERS) data from 2004 to 2020 revealed a notable association between GLP-1 RAs and malignant pancreatic neoplasms (proportional reporting ratio [PRR], 9.86) [52]

Today, these drugs are helping millions of people gain better control over their blood sugar, lose weight, and reduce cardiovascular and other health risks

[1] [2] Tirzepatide (Mounjaro, Zepbound) is a dual GIP/GLP-1 receptor agonist with similar clinical effects

Now for someone using a GLP one medication, this becomes especially important because appetite may be lower and meals may be smaller, and in most of those cases, focusing on low volume, high protein foods can make it easier to reach those targets without feeling overly full

Avoid temperature excursions, since warm temperatures degrade peptides regardless of dose