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Observed outcomes include specific cellular and molecular endpoints such as: Enhanced fibroblast migration capacity Increased collagen and elastin deposition Modulation of pro-inflammatory and antioxidant mediators Altered transcriptional profiles related to tissue homeostasis, repair signaling, and stress response All reported observations derive exclusively from preclinical laboratory and animal studies and remain model-specific

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137 Bruinstroop E, Dalan R, Cao Y, Bee YM, Chandran K, Cho LW, et al

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