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While anti-obesity jabs, which mimic a gut hormone called GLP-1, have been explored in popularity in recent years, they are very expensive

Nguyen VT, Tung NT, Cuong TD et al (2015) Cytotoxic and anti-angiogenic effects of lanostane triterpenoids from Ganoderma lucidum

Optimism over Lillys Zepbound, launched last month, drove a 59% surge in the companys shares last year, making it the largest healthcare firm by market capitalization

10.1038/nm.2452 61 NashineS.KenneyM

In patients with obesity and heart failure with a preserved ejection fraction included in the STEP-HFpEF trial, semaglutide significantly reduced symptoms, improved physical limitations, and enhanced exercise functions compared to placebo (89)

doi: 10.1038/nature16057