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Effects of Ixodes scapularis and Borrelia burgdorferi on modulation of the host immune response: induction of a TH2 cytokine response in Lyme disease-susceptible (C3H/HeJ) mice but not in disease-resistant (BALB/c) mice

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Furthermore, treatment with rhein has effectively reversed alterations in Klotho and TLR4, thereby reducing inflammatory responses ( 2.4.2 Emodin Rheum palmatum is a commonly used herb in TCM for the treatment of AKI