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11.5 Who Should Be Monitored More Closely Monitoring becomes more relevant when: Weight loss exceeds 1520% Appetite suppression leads to persistent under-eating GI symptoms persist Pre-existing marginal status exists Combination therapy (e.g., metformin) is used Older adults are treated Oversight should be proportional to risk

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Once it finally moved, it arrived by two-day delivery, so most of the delay happened before the package ever left the pharmacy

There are other mechanisms by which circulating incretin mimetics can influence deep brain function without crossing the blood-brain barrier