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This article aims to provide a clear and medically grounded overviewfrom basic knowledge and mechanisms to safety considerations and practical guidanceso readers can make informed decisions with confidence

In: Hossain, M., Munn-Bosch, S., Burritt, D., Diaz-Vivancos, P., Fujita, M., Lorence, A

Conventional epigenetic drugs, such as HDAC inhibitors or DNMTi, broadly alter chromatin states and often exhibit substantial off-target effects, limiting their suitability for treating depression or addiction in a targeted manner 196

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