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[22] reported that higher concentrations of eletriptan induced CYP3A in culture medium

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As they are highly reactive, ROS can react with and damage important molecules, such as DNA , lipids (such as those in cell membranes) and proteins (including key enzymes and structural proteins)

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It is important to be aware of these potential side effects and to use tretinoin under the guidance of a dermatologist

Similarly, the phase IIa PBT2 trial demonstrated acceptable safety and modest biomarker modulation without significant clinical efficacy (Ayton et al., 2025)