They, you know, collected data from, like, over 600,000 veterans
Induction of Phase II detoxifying enzymes Reactions catalyzed by phase II detoxifying enzymes generally promote the elimination of drugs, toxins, and carcinogens from the body
As the authors point out, long-term proton pump inhibitor use is connected to serious side effects and increases the risk of some other potentially serious conditions such as Clostridium difficile associated diarrhea, osteoporosis, and vitamin or electrolyte malabsorption
Patients who experience gastrointestinal side effects may require slower dose escalation, which delays reaching therapeutic doses but does not prevent eventual weight loss success
Most are gastrointestinal, tend to be mild to moderate, and often improve as your body adjusts and as the dose is increased slowly
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