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335 Astrocytes in post-mortem samples of patients with mesial temporal lobe epilepsy show significant down-regulation of K ir 4.1 channels critical for K + buffering

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Of the adverse experiences judged to be of "possible" relationship to the study drug, anxiety, incoordination, and nervousness were reported following intramuscular vitamin B12 and headache, nausea, and rhinitis were reported following dosing with Nascobal (Cyanocobalamin, USP) Gel for Intranasal Administration

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The DAC variant requires additional care to avoid thiol-containing reagents and alkaline conditions