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When symptomatic, patients may present with fatigue, oedema, headaches and severe anaemia disproportionate to impairment of kidney function [31]

Such modulators include thyroid hormone, GLP-1, and leptin (109, 110)

In addition to the full report and summary of findings released today, Health Affairs is publishing an article with select findings online

Patients who should NOT use it include those with uncontrolled diabetes, active malignancy or personal history of hormone-sensitive cancer, or pituitary disease

Managing constipation on tirzepatide , body aches , and other common side effects has become well-established through clinical experience