Importantly, it enabled discrimination between human-specific and animal-specific toxicities, such as those induced by bosentan (an endothelin receptor antagonist with known dose-dependent human hepatotoxicity) and fialuridine (an antiviral nucleoside analog that caused fatal human liver toxicity undetected in animals), thereby improving the extrapolation of preclinical findings to human outcomes
vivax in areas where effective malaria control programmes have been implemented [7]
Categorical data were described using frequencies and percentages, and differences between groups were analyzed using the chi-square test or Fishers exact test
Neurotoxicology 45:131138 Duan J, Xiaokaiti Y, Fan S, Pan Y, Li X, Li X (2017) Direct interaction between caffeic acid phenethyl ester and human neutrophil elastase inhibits the growth and migration of PANC-1 cells
Waikar SS, Srivastava A, Palsson R, Shafi T, Hsu CY, Sharma K, et al
Research conducted in animal models has shown that BPC-157 can accelerate the healing of muscles, tendons, ligaments, and even the gut lining