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By June 2021, synthetic opioids were involved in an estimated 87% of opioid deaths and 65% of all drug overdose deaths.(5) This has made opioid overdose a leading cause of death in the United States.(6) Figures 1 and 2: NIDA, Drug Overdose Deaths: Facts and Figures, Fentanyl Fentanyl is 50 times more potent than heroin and 100 times more potent than morphine

Regular laboratory monitoring helps prevent serious complications

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10 Importantly, this suppression is not observed during daytime fasting when gut hormone secretion is reduced, 14 highlighting direct effects of peptide hormones on bone turnover in response to nutritional status

as later sections explain, it is precisely the property that makes the no-DAC form the version selected for a blend intended to reinforce discrete natural pulses