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These drugs are not FDA approved and are subject to limited agency oversight

According to a study presented at the 2025 Society of Hematologic Oncology (SOHO) meeting, patients with PV who received GLP-1 therapy experienced : - *Reduced All-Cause Mortality*: Lower odds of death from any cause - *Lower Rates of Myelofibrosis Progression*: Decreased risk of progression to myelofibrosis, a condition where scar tissue builds up in the bone marrow - *Decreased Venous Thromboembolism (VTE)*: Fewer blood clots - *Fewer Hospitalizations*: Reduced need for hospitalization - *Reduced Risk of Acute Kidney Injury and Ischemic Stroke*: Lower risk of kidney damage and stroke

The review highlighted the importance of choosing well-studied strains with demonstrated ability to survive the stomach environment and reach the gut intact

Refrigeration at 28C is insufficient for long-term stability of lyophilised peptides