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[13] [14] Patients with a personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2 should not receive GLP-1 medications due to the theoretical risk of thyroid C-cell tumors

Upon immunohistochemical study, dendritic cells in the basal layer of glands were found to be positive for S-100 protein (1:1,000, Dako, Glostrup, Denmark), but were negative for human melanoma black-45 (HMB-45

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Patients can try taking their medication with food or starting with a lower dose and gradually increasing it at the discretion of their prescriber

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1, which exemplifies how redox changes modulate cellular defense responses