Heat exposure degrades the peptide structure, reducing tirzepatide's appetite-suppression and blood-sugar-control effects
If approved, orforglipron would be the first oral medication that directly competes with injectable GLP-1 therapies on efficacy
Weight loss in elderly patients carries different considerations than in younger adults
A previous study examining real-world outcomes of long-term therapy with AOMs reported that patients taking phentermine-topiramate had a TBWL% of 12% at 12 months, as compared to 5.61% for liraglutide [24]
The Bioenergetic Crisis of the Menopause Transition The hormonal shifts of menopause are often described in terms of what is lost: estrogen falls, progesterone declines, and the reproductive system transitions out of its active phase
More frequent monitoring may be needed during pregnancy, with significant weight changes, or when medications affecting thyroid hormone metabolism are started or stopped