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Under in vitro conditions, graphene oxide quantum dots alleviated 1-methyl-4-phenyl-pyridinium ion (MPP + )-induced oxidative stress and apoptosis

The initial reaction rates at different concentrations of compound were used to determine EC 50 values, which were calculated with a four-parameter logistical model of log dose against percentage activation and were obtained from at least three sets of experiments

They support the bodys natural production of glutathione, which can be a gentler and more sustainable approach

Baltimore, Md.: Lippincott Williams & Wilkins

The following databases were searched: Ovid MEDLINE, MEDLINE In-Process and Other Non-Indexed Citations, Ovid Embase, Wiley Cochrane, EBSCO Cumulative Index to Nursing & Allied Health Literature (CINAHL), and Centre for Reviews and Dissemination/International Agency for Health Technology Assessment

The levels of GSH was slightly reduced in MPP + -treated SHSY-5Y cells, which was further restored to baseline levels by Sp, together with accompanying decrease in accumulated GSSG (Fig