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Das subkutan zu verabreichende Medikament ist in der Schweiz zugelassen

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and the incidences of adrenocortical carcinomas and combined adrenocortical adenomas/carcinomas were increased at an oral dose of 60 mg/kg/day (14 times human exposure at MRHD based on AUC and 19 times the MRHD based on mg/m2)

APT2 inhibition restores scribble localization and S -palmitoylation in snail-transformed cells