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For the targeted sulfur metabolite quantification approach, the previously established LC-MS conditions were applied 99 with selected reaction monitoring (MRM) using an Ultimate 3000 UPLC system coupled to a Thermo Finnigan TSQ Quantum equipped with HESI (Thermo Fisher Scientific, Waltham, MA)

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10b, combined tumor growth inhibition curves: Fig

Notably, Homocysteine can react and modify specific proteins, resulting in neo-antigens development and autoimmunity development (Lazzerini et al

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