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When patients understand that joint pain may reflect positive metabolic change rather than medication toxicity, they are more likely to continue treatment and incorporate supportive strategies

The class evidence (STEP for semaglutide, 2021

Even though a meta-analysis reported an increase in cardiovascular mortality linked to the use of TZDs in dialysis patients (Nissen and Wolski, 2007), no definitive proof are available on the risk related to this medication in this population

Disordered eating warrants special attention

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