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Conversely, ghrelin binding its receptor activates AgRP and NPY neurons, resulting in an increase in GABA release with resultant inhibition of POMC neurons

Some probiotics can reduce the production of reactive oxygen species, enhance the activity of superoxide dismutase, glutathione peroxidase and other antioxidant enzymes (Ghoneim and Moselhy, 2016

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Furthermore, a balanced gut reduces the overall "toxic load" on the liver

doi:10.1016/j.biopsych.2004.11.006 McLaughlin KA, Fox NA, Zeanah CH, Sheridan MA, Marshall P, Nelson CA