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It is plausible that excessive ROS from other metabolic disorders (such as obesity, insulin resistance, and elevated LDL-cholesterol and low HDL-cholesterol) can induce a state of chronic low-grade inflammation (e.g., raising IFN- and TNF-), possibly aggravating or activating vitiligo in genetically predisposed individuals, as illustrated in Figure 1

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Our multimodal treatment with antioxidants was therefore suspended

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