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In the modern era, isolated nutrients like choline and the amino acid taurine have been studied extensively for their nootropic benefits, and are known to work synergistically with herbs

Ohashi R, Tamai I, Inano A, et al

Therefore, oral administration of a single dose of 2.5 mg/kg of l-theanine or 2.0 mg/kg of caffeine is very unlikely to result in an adverse event even among children

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Understanding these differences is essential for making informed treatment decisions