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In conclusion, the BP lowering effect of DPP-4i may be reduced by stimulating sympathetic activity via reducing degradation of GLP-1 and substance P when combined with ACEI, especially in high-dose ACEI

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3H, in the presence of FeSO 4 7H 2 O and H 2 O 2 , a significant color change from colorless TMB to its blue product oxTMB was observed in control groups, and an absorbance at 652 nm was also measured