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Glucagon-like peptide-1 is an incretin hormone known for its ability to lower your blood sugar levels, especially after eating and during fasting, by acting on organs like your pancreas and brain

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Blood was collected from tail vein at 0 min, followed by i.p

However, studies have reported side effects like gastrointestinal discomfort, nutritional deficiencies due to poor eating, muscle loss, and weight regain after treatments end

demonstrated that although the combination therapy (metformin 1000 mg BID + liraglutide 1.2 mg/day) resulted in a greater weight loss than liraglutide alone, both groups showed an increase in SHBG and a decrease in free testosterone, with no differences between the two treatment arms, thus suggesting that the effect on the biochemical hyperandrogenism of liraglutide may be partially independent of the extent of weight loss [60]