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Conclusions In patients with overweight or obesity and without T2DM, treatment with semaglutide 2.4 mg and tirzepatide was associated with 14.1% and 16.5% weight loss, respectively, after a 1-year follow-up period, indicating the effectiveness of these therapies in routine clinical practice in the US

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Clinical trials demonstrate that pairing these two medications can enhance glucose control while supporting sustainable weight management without requiring significant dose adjustments to either drug

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Still, some patients with early-stage breast cancer face a continuous risk of recurrence