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The exclusion criteria were: Studies not involving the pancreas or PACs (for example, studies limited to other organs or cancer cell lines without direct relevance to AP pathogenesis)

This metaboloepigenetic rewiring is called metabostemness [80]

doi: 10.1007/s10545-015-9843-7

Similarly, tirzepatide, another GLP-1 and GIP receptor agonist (branded as Mounjaro for diabetes and Zepbound for weight loss), shares many of semaglutides mechanisms and considerations

n = 3/sex for 2 and 6 mg/kg)