2019 Jan 7;10(1):7-16
Upon activation of the GLP1R, inhibition of the RhoA/ROCK signalling pathway reduces the phosphorylation of myosin light chain (MLC), thereby maintaining the integrity of tight junction proteins such as Occludin and ZO1, and protecting the BRB from hyperglycaemia-induced damage [52]
clinicaltrials.gov/study/NCT05929066
*Correspondence: Yi Cai, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers
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