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doi: 10.1056/NEJM199404143301501 80

A 2017 study published in Oncotarget has also noted that the effects of berberine on cholesterol may be similar to metformin but without the side effects of the medication ( 16 )

Overexcitation of NMDA R by excessive glutamate release or impaired synaptic clearance leads to the death of neurons by excitotoxicity (70)