cancer glutathione Functions of glutathione-degrading enzymes in tumors. The functions of Metabolic orchestration driven by GGCT:

Glutathione protects cells from the oxidative stress that iron can create

ROS react with biological molecules (lipids, proteins, nucleic acids, carbohydrates), producing new oxidative species, which trigger oxidative chain reactions of other macromolecules

Its primary function is to combat oxidative stress by neutralizing free radicals, thereby protecting cells from damage

Seregina T, Shakulov R, Shatalin K, et al

Glutathione is a powerful antioxidant naturally produced by your body

The mTORC1 inhibition by AMPK is accomplished by direct phosphorylation of the regulatory-associated protein of mTOR (Raptor) [264] and indirectly via activation of TSC2 [265, 266]