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A SUSTAIN 10 trial evaluated 577 adults with type 2 diabetes to compare how semaglutide (1 mg weekly) and liraglutide (1.2 mg daily) affected blood sugar and body weight over 30 weeks

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After 3 months, women who increased FV intake by 3 or more servings experienced significant improvements in insomnia-related sleep difficulties compared to those with no change or a decrease in FV intake [147]

Its lead liver asset, obeticholic acid, was pushed for NASH (MASH's old name) and was rejected by the FDA twice despite producing statistically significant fibrosis data, because the agency wasn't satisfied on the totality of benefit-versus-risk

Rather than being a harmful side effect, these changes reflect how Mounjaro improves insulin response and reduces glucose levels

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