Previous studies have found that activation of TRPV1 can significantly reduce cartilage degeneration by upregulating GPX4 and eliminating ferroptosis in chondrocytes
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Unlike acquired melanocytic nevi and solar lentigo, lentigo simplex lesions are not associated with mutations of BRAF (V600E), PIK3CA, or FGFR3 (30)
Proteomics data analysis A Comprehensive data management procedure encompassing three key steps was carried out to ensure the robustness and comparability of our dataset
Determination of malondialdehyde Malondialdehyde (MDA) was measured according to the method described by (Sastre, Pallard, Asuncion, & Vina, 2000)