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Skeletal muscle, ligament, and bone-defect models have produced comparable healing-rate findings, summarized in the 2021 wound-healing review (PMID 34267654) and the 2025 musculoskeletal narrative review (PMID 40789979)

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Even determining which form of the drug should be used was unclear to regulators, since BPC-157 is not recognized as an official pharmaceutical ingredient in the U.S