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TLDR summary - On top of UVR protective benefits, Colourless Carotenoids have additional cosmetic and health benefits such as antioxidant, anti-inflammatory, anti-carcinogenic, skin lightening and anti-ageing

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The combination of large extracellular domains (ECD), extended orthosteric binding sites, and conformational flexibility makes class B1 GPCRs interesting but challenging targets for rational ligand discovery and particularly demanding benchmarks for computational ligand design and virtual screening methodologies (Aksu et al., 2024

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Recently, Ma et al