Mirroring data from sAC / mice, depletion of sAC in human caSMCs through a siRNA also abrogated cAMP responses to GLP-1(2836) (Figure 2I), providing further evidence of a nonreceptor, sAC-dependent mechanism
Sin embargo, con el tiempo, se observaron efectos secundarios inesperados : alteraciones en la absorcin de nutrientes, deficiencias hormonales, dificultades para sostener el embarazo y riesgos para el desarrollo fetal
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