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Side effects depend on the active ingredient and dose, not the source of compounding

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In other words, any benefits gained over the course of taking GLP-1 medications are quickly lost when patients stop

FDA adverse event data (as of early 2025) 455+ adverse event reports linked to compounded semaglutide 320+ adverse event reports linked to compounded tirzepatide Many involved dosing errors from multidose vials, some requiring hospitalization Reports include severe nausea, vomiting, dehydration, and overdose symptoms Documented contamination, mislabeling, and counterfeit product cases 1

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